Cargando…
Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway
Podocyte mitochondrial dysfunction plays a critical role in the pathogenesis of chronic kidney disease (CKD). Previous studies demonstrated that excessive mitochondrial fission could lead to the overproduction of reactive oxygen species (ROS) and promote podocyte apoptosis. Therefore, the maintenanc...
Autores principales: | Zhu, Zijing, Liang, Wei, Chen, Zhaowei, Hu, Jijia, Feng, Jun, Cao, Yun, Ma, Yiqiong, Ding, Guohua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380182/ https://www.ncbi.nlm.nih.gov/pubmed/34426758 http://dx.doi.org/10.1155/2021/1394486 |
Ejemplares similares
-
AKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease
por: Feng, Jun, et al.
Publicado: (2022) -
Alteration in Rab11‐mediated endocytic trafficking of LDL receptor contributes to angiotensin II‐induced cholesterol accumulation and injury in podocytes
por: Hu, Jijia, et al.
Publicado: (2022) -
PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment
por: Huang, Xiaoxiao, et al.
Publicado: (2023) -
Sestrin-2 regulates podocyte mitochondrial dysfunction and apoptosis under high-glucose conditions via AMPK
por: Lin, Qiaoxuan, et al.
Publicado: (2020) -
Sirt6 deficiency contributes to mitochondrial fission and oxidative damage in podocytes via ROCK1‐Drp1 signalling pathway
por: Chen, Zhaowei, et al.
Publicado: (2022)