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One-pot and one-step automated radio-synthesis of [(18)F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

BACKGROUND: Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [(18)F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [(18)F]AlF-FA...

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Detalles Bibliográficos
Autores principales: Naka, Sadahiro, Watabe, Tadashi, Lindner, Thomas, Cardinale, Jens, Kurimoto, Kenta, Moore, Melissa, Tatsumi, Mitsuaki, Mori, Yuriko, Shimosegawa, Eku, Valla, Frank, Kato, Hiroki, Giesel, Frederik L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380200/
https://www.ncbi.nlm.nih.gov/pubmed/34420105
http://dx.doi.org/10.1186/s41181-021-00142-z