Potential and pitfalls of (89)Zr-immuno-PET to assess target status: (89)Zr-trastuzumab as an example

BACKGROUND: (89)Zirconium-immuno-positron emission tomography ((89)Zr-immuno-PET) is used for assessment of target status to guide antibody-based therapy. We aim to determine the relation between antibody tumor uptake and target concentration to improve future study design and interpretation. METHOD...

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Detalles Bibliográficos
Autores principales: Huisman, Marc C., Menke-van der Houven van Oordt, C. Willemien, Zijlstra, Josée M., Hoekstra, Otto S., Boellaard, Ronald, van Dongen, Guus A. M. S., Shah, Dhaval K., Jauw, Yvonne W. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380210/
https://www.ncbi.nlm.nih.gov/pubmed/34417917
http://dx.doi.org/10.1186/s13550-021-00813-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380210/
https://www.ncbi.nlm.nih.gov/pubmed/34417917
http://dx.doi.org/10.1186/s13550-021-00813-7

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