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GABA(A) receptors: structure, function, pharmacology, and related disorders

BACKGROUND: γ-Aminobutyric acid sub-type A receptors (GABA(A)Rs) are the most prominent inhibitory neurotransmitter receptors in the CNS. They are a family of ligand-gated ion channel with significant physiological and therapeutic implications. MAIN BODY: GABA(A)Rs are heteropentamers formed from a...

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Detalles Bibliográficos
Autores principales: Ghit, Amr, Assal, Dina, Al-Shami, Ahmed S., Hussein, Diaa Eldin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380214/
https://www.ncbi.nlm.nih.gov/pubmed/34417930
http://dx.doi.org/10.1186/s43141-021-00224-0