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microRNA-29b prevents renal fibrosis by attenuating renal tubular epithelial cell–mesenchymal transition through targeting the PI3K/AKT pathway

PURPOSE: This study aimed to investigate the effects of miR-29b on renal interstitial fibrosis in the obstructed kidney of mouse with unilateral ureteral obstruction (UUO) via inhibiting phosphatidylinositol 3-kinase/protein kinaseB (PI3K/AKT) signaling pathway. METHODS: Adult male CD-1 mice were in...

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Detalles Bibliográficos
Autores principales: Hu, Shuang, Hu, Hongtao, Wang, Rui, He, Hong, Shui, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380229/
https://www.ncbi.nlm.nih.gov/pubmed/33742315
http://dx.doi.org/10.1007/s11255-021-02836-4