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Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes

Drug-induced liver injury (DILI) is an adverse toxic hepatic clinical reaction associated to the administration of a drug that can occur both at early clinical stages of drug development, as well after normal clinical usage of approved drugs. Because of its unpredictability and clinical relevance, i...

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Detalles Bibliográficos
Autores principales: Quintás, Guillermo, Martínez-Sena, Teresa, Conde, Isabel, Pareja Ibars, Eugenia, Kleinjans, Jos, Castell, José V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380240/
https://www.ncbi.nlm.nih.gov/pubmed/34274980
http://dx.doi.org/10.1007/s00204-021-03114-z