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NF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1

BACKGROUND: H. pylori infection is the main risk factor for gastric cancer. In this study, we investigated H. pylori-mediated activation of STAT3 and NF-κB in gastric cancer, using in vitro and in vivo models. METHODS: To investigate the activation of NF-κB and STAT3 by H. pylori strains we used in...

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Detalles Bibliográficos
Autores principales: Soutto, Mohammed, Bhat, Nadeem, Khalafi, Shayan, Zhu, Shoumin, Poveda, Julio, Garcia-Buitrago, Monica, Zaika, Alexander, El-Rifai, Wael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380333/
https://www.ncbi.nlm.nih.gov/pubmed/34419066
http://dx.doi.org/10.1186/s12935-021-02140-2