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Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue

BACKGROUND: DNA methylation is involved in the regulation of gene expression and phenotypic variation, but the inter-relationship between genetic variation, DNA methylation and gene expression remains poorly understood. Here we combine the analysis of genetic variants related to methylation markers...

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Detalles Bibliográficos
Autores principales: Díez-Villanueva, Anna, Jordà, Mireia, Carreras-Torres, Robert, Alonso, Henar, Cordero, David, Guinó, Elisabet, Sanjuan, Xavier, Santos, Cristina, Salazar, Ramón, Sanz-Pamplona, Rebeca, Moreno, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380335/
https://www.ncbi.nlm.nih.gov/pubmed/34419169
http://dx.doi.org/10.1186/s13148-021-01148-9