A Novel High-Content Screening-Based Method for Anti-Trypanosoma cruzi Drug Discovery Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Chagas disease is caused by Trypanosoma cruzi infection and remains a relevant cause of chronic heart failure in Latin America. The pharmacological arsenal for Chagas disease is limited, and the available anti-T. cruzi drugs are not effective when administered during the chronic phase. Cardiomyocyte...

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Detalles Bibliográficos
Autores principales: Portella, Diogo Crispim Nascimento, Rossi, Erik Aranha, Paredes, Bruno Diaz, Bastos, Tanira Matutino, Meira, Cássio Santana, Nonaka, Carolina Vasques Kymie, Silva, Daniela Nascimento, Improta-Caria, Alex, Moreira, Diogo Rodrigo Magalhaes, Leite, Ana Cristina Lima, de Oliveira Filho, Gevanio Bezerra, Filho, José Maria Barbosa, dos Santos, Ricardo Ribeiro, Soares, Milena Botelho Pereira, Souza, Bruno Solano de Freita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380504/
https://www.ncbi.nlm.nih.gov/pubmed/34434238
http://dx.doi.org/10.1155/2021/2642807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380504/
https://www.ncbi.nlm.nih.gov/pubmed/34434238
http://dx.doi.org/10.1155/2021/2642807

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