Cystathionine β-synthase mediated PRRX2/IL-6/STAT3 inactivation suppresses Tregs infiltration and induces apoptosis to inhibit HCC carcinogenesis

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by inflammation and immunopathogenesis. Accumulating evidence has shown that the cystathionine β-synthase/hydrogen sulfide (CBS/H(2)S) axis is involved in the regulation of inflammation. However, roles of CBS in HCC development and immune e...

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Detalles Bibliográficos
Autores principales: Zhou, Yu-Fu, Song, Shu-Shu, Tian, Meng-Xin, Tang, Zheng, Wang, Han, Fang, Yuan, Qu, Wei-Feng, Jiang, Xi-Fei, Tao, Chen-Yang, Huang, Run, Zhou, Pei-Yun, Zhu, Shi-Guo, Zhou, Jian, Fan, Jia, Liu, Wei-Ren, Shi, Ying-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380548/
https://www.ncbi.nlm.nih.gov/pubmed/34413167
http://dx.doi.org/10.1136/jitc-2021-003031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380548/
https://www.ncbi.nlm.nih.gov/pubmed/34413167
http://dx.doi.org/10.1136/jitc-2021-003031

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