IL‐38 prevents induction of trained immunity by inhibition of mTOR signaling

Trained immunity is the acquisition of a hyperresponsive phenotype by innate immune cells (such as monocytes and macrophages) after an infection or vaccination, a de facto nonspecific memory dependent on epigenetic and metabolic reprogramming of these cells. We have recently shown that induction of...

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Detalles Bibliográficos
Autores principales: de Graaf, Dennis M., Teufel, Lisa U., van de Veerdonk, Frank L., Joosten, Leo A. B., Netea, Mihai G., Dinarello, Charles A., Arts, Rob J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Inflammation, Extracellular Mediators, and Effector Molecules
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380748/
https://www.ncbi.nlm.nih.gov/pubmed/33620105
http://dx.doi.org/10.1002/JLB.3A0220-143RRR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380748/
https://www.ncbi.nlm.nih.gov/pubmed/33620105
http://dx.doi.org/10.1002/JLB.3A0220-143RRR

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