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ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells

Mitochondrial injury of tubular epithelial cells (TECs) is the key pathogenic event underlying various kidney diseases and a potential intervening target as well. Our previous study demonstrated that ING2 is ubiquitously expressed at tubulointerstitial area within kidneys, while its role in regulati...

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Detalles Bibliográficos
Autores principales: Yang, Ying, Li, Chensheng, Gu, Xia, Zhen, Junhui, Zhu, Suwei, Lv, Tingting, Wan, Qiang, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8380824/
https://www.ncbi.nlm.nih.gov/pubmed/34434929
http://dx.doi.org/10.3389/fcell.2021.700195