ADAMTS5 in Osteoarthritis: Biological Functions, Regulatory Network, and Potential Targeting Therapies

ADAMTS5 is involved in the pathogenesis of OA. As the major aggrecanase-degrading articular cartilage matrix, ADAMTS5, has been regarded as a potential target for OA treatment. We here provide an updated insight on the regulation of ADAMTS5 and newly discovered therapeutic strategies for OA. Pathoph...

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Detalles Bibliográficos
Autores principales: Jiang, Lejian, Lin, Jiachen, Zhao, Sen, Wu, Jiaqian, Jin, Yongming, Yu, Li, Wu, Nan, Wu, Zhihong, Wang, Yue, Lin, Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381022/
https://www.ncbi.nlm.nih.gov/pubmed/34434966
http://dx.doi.org/10.3389/fmolb.2021.703110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381022/
https://www.ncbi.nlm.nih.gov/pubmed/34434966
http://dx.doi.org/10.3389/fmolb.2021.703110

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