Nerve Growth Factor Compromise in Down Syndrome

The basal forebrain cholinergic system relies on trophic support by nerve growth factor (NGF) to maintain its phenotype and function. In Alzheimer’s disease (AD), basal forebrain cholinergic neurons (BFCNs) undergo progressive atrophy, suggesting a deficit in NGF trophic support. Within the central...

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Detalles Bibliográficos
Autores principales: Do Carmo, Sonia, Kannel, Benjamin, Cuello, A. Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381049/
https://www.ncbi.nlm.nih.gov/pubmed/34434101
http://dx.doi.org/10.3389/fnagi.2021.719507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381049/
https://www.ncbi.nlm.nih.gov/pubmed/34434101
http://dx.doi.org/10.3389/fnagi.2021.719507

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