Long-term effect of α(1)-antitrypsin augmentation therapy on the decline of FEV(1) in deficient patients: an analysis of the AIR database

BACKGROUND: Patients with ZZ (Glu342Lys) α-1-antitrypsin deficiency (ZZ-AATD) who received augmentation therapy with α-1-antitrypsin (AAT) in randomised controlled trials over 2–3 years failed to show a significant reduction of the annual decline of forced expiratory volume in 1 s (FEV(1)). METHODS:...

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Detalles Bibliográficos
Autores principales: Schouten, Iris G.M., Kasteleyn, Marise J., Tsonaka, Roula, Bals, Robert, Turner, Alice C., Ferrarotti, Ilaria, Corsico, Angelo G., Lara, Beatriz, Miravitlles, Marc, Stockley, Robert A., Stolk, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381156/
https://www.ncbi.nlm.nih.gov/pubmed/34435030
http://dx.doi.org/10.1183/23120541.00194-2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381156/
https://www.ncbi.nlm.nih.gov/pubmed/34435030
http://dx.doi.org/10.1183/23120541.00194-2021

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