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Acromegaly Cases Exhibiting Increased Growth Hormone Levels during Oral Glucose Loading with Preadministration of Dipeptidyl Peptidase-4 Inhibitor

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) is speculated to worsen growth hormone (GH) hypersecretion in acromegaly and to be a cause of paradoxical increases in GH (PI-GH) during 75-g oral glucose tolerance testing (75-g OGTT). Dipeptidyl peptidase-4 inhibitors (DPP4is), which in...

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Detalles Bibliográficos
Autores principales: Oba-Yamamoto, Chiho, Kameda, Hiraku, Miyoshi, Hideaki, Sekizaki, Tomonori, Takase, Takahiro, Yanagimachi, Tsuyoshi, Fujita, Yukihiro, Nomoto, Hiroshi, Cho, Kyu Yong, Nakamura, Akinobu, Nagai, So, Atsumi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381171/
https://www.ncbi.nlm.nih.gov/pubmed/34334589
http://dx.doi.org/10.2169/internalmedicine.4755-20