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Comparison of Pinoresinol and its Diglucoside on their ADME Properties and Vasorelaxant Effects on Phenylephrine-Induced Model

Pinoresinol (PINL) and pinoresinol diglucoside (PDG), two natural lignans found in Eucommia ulmoides Oliv. (Duzhong), have several pharmacological activities. However, there is no report available on their absorption, distribution, metabolism, and elimination (ADME) properties. Given the possible wi...

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Detalles Bibliográficos
Autores principales: Pu, Yiqiong, Cai, Yiqing, Zhang, Qi, Hou, Tianling, Zhang, Teng, Zhang, Tong, Wang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381248/
https://www.ncbi.nlm.nih.gov/pubmed/34434107
http://dx.doi.org/10.3389/fphar.2021.695530