A Computational Approach to Evaluate the Combined Effect of SARS-CoV-2 RBD Mutations and ACE2 Receptor Genetic Variants on Infectivity: The COVID-19 Host-Pathogen Nexus

SARS-CoV-2 infectivity is largely determined by the virus Spike protein binding to the ACE2 receptor. Meanwhile, marked infection rate differences were reported between populations and individuals. To understand the disease dynamic, we developed a computational approach to study the implications of...

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Detalles Bibliográficos
Autores principales: Ashoor, Dana, Ben Khalaf, Noureddine, Marzouq, Maryam, Jarjanazi, Hamdi, Chlif, Sadok, Fathallah, M. Dahmani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381355/
https://www.ncbi.nlm.nih.gov/pubmed/34434902
http://dx.doi.org/10.3389/fcimb.2021.707194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381355/
https://www.ncbi.nlm.nih.gov/pubmed/34434902
http://dx.doi.org/10.3389/fcimb.2021.707194

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