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Hearing Loss in Id1(−/−); Id3(+/−) and Id1(+/−); Id3(−/−) Mice Is Associated With a High Incidence of Middle Ear Infection (Otitis Media)

Inhibitors of differentiation/DNA binding (Id) proteins are crucial for inner ear development, but whether Id mutations affect middle ear function remains unknown. In this study, we obtained Id1(−/−); Id3(+/−) mice and Id1(+/−); Id3(−/−) mice and carefully examined their middle ear morphology and au...

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Detalles Bibliográficos
Autores principales: Zheng, Qingyin, Zheng, Tihua, Zhang, Aizhen, Yan, Bin, Li, Bo, Zhang, Zhaoqiang, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381378/
https://www.ncbi.nlm.nih.gov/pubmed/34434211
http://dx.doi.org/10.3389/fgene.2021.508750