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The lncRNA CASC9 alleviates lipopolysaccharide-induced acute kidney injury by regulating the miR-424-5p/TXNIP pathway

OBJECTIVE: This study aimed to clarify the mechanism by which the long non-coding RNA cancer susceptibility candidate 9 (CASC9) alleviates sepsis-related acute kidney injury (S-AKI). METHODS: A lipopolysaccharide (LPS)-induced AKI model was established to simulate S-AKI. HK-2 human renal tubular epi...

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Detalles Bibliográficos
Autores principales: Fan, Hai-Peng, Zhu, Zhi-Xia, Xu, Jia-Jun, Li, Yu-Tang, Guo, Chun-Wen, Yan, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381429/
https://www.ncbi.nlm.nih.gov/pubmed/34407684
http://dx.doi.org/10.1177/03000605211037495