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Oleic Acid and Insulin as Key Characteristics of T2D Promote Colorectal Cancer Deterioration in Xenograft Mice Revealed by Functional Metabolomics

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers with high mortality worldwide. Type 2 diabetes mellitus (T2D), known as a risk factor of CRC, can promote the deterioration of CRC, but the underlying mechanism is elusive. In this study, we aimed to reveal the relationship betwee...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Wang, Di, Lv, Bo, Hou, Xiaoying, Liu, Qiwei, Liao, Chuyao, Xu, Ruijie, Zhang, Yuxin, Xu, Fengguo, Zhang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381473/
https://www.ncbi.nlm.nih.gov/pubmed/34434893
http://dx.doi.org/10.3389/fonc.2021.685059