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Pre-implantation alcohol exposure induces lasting sex-specific DNA methylation programming errors in the developing forebrain

BACKGROUND: Prenatal alcohol exposure is recognized for altering DNA methylation profiles of brain cells during development, and to be part of the molecular basis underpinning Fetal Alcohol Spectrum Disorder (FASD) etiology.  However, we have negligible information on the effects of alcohol exposure...

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Detalles Bibliográficos
Autores principales: Legault, L. M., Doiron, K., Breton-Larrivée, M., Langford-Avelar, A., Lemieux, A., Caron, M., Jerome-Majewska, L. A., Sinnett, D., McGraw, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381495/
https://www.ncbi.nlm.nih.gov/pubmed/34425890
http://dx.doi.org/10.1186/s13148-021-01151-0