Estimation of total mediation effect for high-dimensional omics mediators

BACKGROUND: Environmental exposures can regulate intermediate molecular phenotypes, such as gene expression, by different mechanisms and thereby lead to various health outcomes. It is of significant scientific interest to unravel the role of potentially high-dimensional intermediate phenotypes in th...

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Detalles Bibliográficos
Autores principales: Yang, Tianzhong, Niu, Jingbo, Chen, Han, Wei, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381496/
https://www.ncbi.nlm.nih.gov/pubmed/34425752
http://dx.doi.org/10.1186/s12859-021-04322-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381496/
https://www.ncbi.nlm.nih.gov/pubmed/34425752
http://dx.doi.org/10.1186/s12859-021-04322-1

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