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Serum-free medium and hypoxic preconditioning synergistically enhance the therapeutic effects of mesenchymal stem cells on experimental renal fibrosis

BACKGROUND: Mesenchymal stem cells (MSCs) repair injured tissue in a paracrine manner. To enhance their therapeutic properties, preconditioning with various factors has been researched. We have previously showed that MSCs cultured in serum-free medium (SF-MSCs) promote their immunosuppressive abilit...

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Detalles Bibliográficos
Autores principales: Ishiuchi, Naoki, Nakashima, Ayumu, Doi, Shigehiro, Kanai, Ryo, Maeda, Satoshi, Takahashi, Shinya, Nagao, Masataka, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381539/
https://www.ncbi.nlm.nih.gov/pubmed/34425892
http://dx.doi.org/10.1186/s13287-021-02548-7