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Serum-free medium and hypoxic preconditioning synergistically enhance the therapeutic effects of mesenchymal stem cells on experimental renal fibrosis
BACKGROUND: Mesenchymal stem cells (MSCs) repair injured tissue in a paracrine manner. To enhance their therapeutic properties, preconditioning with various factors has been researched. We have previously showed that MSCs cultured in serum-free medium (SF-MSCs) promote their immunosuppressive abilit...
Autores principales: | Ishiuchi, Naoki, Nakashima, Ayumu, Doi, Shigehiro, Kanai, Ryo, Maeda, Satoshi, Takahashi, Shinya, Nagao, Masataka, Masaki, Takao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381539/ https://www.ncbi.nlm.nih.gov/pubmed/34425892 http://dx.doi.org/10.1186/s13287-021-02548-7 |
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