Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis

Antibacterial agents target the products of essential genes but rarely achieve complete target inhibition. Thus, the all-or-none definition of essentiality afforded by traditional genetic approaches fails to discern the most attractive bacterial targets: those whose incomplete inhibition results in...

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Detalles Bibliográficos
Autores principales: Bosch, Barbara, DeJesus, Michael A., Poulton, Nicholas C., Zhang, Wenzhu, Engelhart, Curtis A., Zaveri, Anisha, Lavalette, Sophie, Ruecker, Nadine, Trujillo, Carolina, Wallach, Joshua B., Li, Shuqi, Ehrt, Sabine, Chait, Brian T., Schnappinger, Dirk, Rock, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382161/
https://www.ncbi.nlm.nih.gov/pubmed/34297925
http://dx.doi.org/10.1016/j.cell.2021.06.033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382161/
https://www.ncbi.nlm.nih.gov/pubmed/34297925
http://dx.doi.org/10.1016/j.cell.2021.06.033

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