Cargando…

Cell-cell adhesion regulates Merlin/NF2 interaction with the PAF complex

The PAF complex (PAFC) coordinates transcription elongation and mRNA processing and its CDC73/parafibromin subunit functions as a tumour suppressor. The NF2/Merlin tumour suppressor functions both at the cell cortex and nucleus and is a key mediator of contact inhibition but the molecular mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Roehrig, Anne E., Klupsch, Kristina, Oses-Prieto, Juan A., Chaib, Selim, Henderson, Stephen, Emmett, Warren, Young, Lucy C., Surinova, Silvia, Blees, Andreas, Pfeiffer, Anett, Tijani, Maha, Brunk, Fabian, Hartig, Nicole, Muñoz-Alegre, Marta, Hergovich, Alexander, Jennings, Barbara H., Burlingame, Alma L., Rodriguez-Viciana, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382200/
https://www.ncbi.nlm.nih.gov/pubmed/34424918
http://dx.doi.org/10.1371/journal.pone.0254697