Cargando…

Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core

[Image: see text] An azide-functionalized 12-armed Buckminster fullerene has been monosubstituted in organic media with a substoichiometric amount of cyclooctyne-modified oligonucleotides. Exposing the intermediate products then to the same reaction (i.e., strain-promoted alkyne–azide cycloaddition,...

Descripción completa

Detalles Bibliográficos
Autores principales: Gulumkar, Vijay, Äärelä, Antti, Moisio, Olli, Rahkila, Jani, Tähtinen, Ville, Leimu, Laura, Korsoff, Niko, Korhonen, Heidi, Poijärvi-Virta, Päivi, Mikkola, Satu, Nesati, Victor, Vuorimaa-Laukkanen, Elina, Viitala, Tapani, Yliperttula, Marjo, Roivainen, Anne, Virta, Pasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382215/
https://www.ncbi.nlm.nih.gov/pubmed/33998229
http://dx.doi.org/10.1021/acs.bioconjchem.1c00187