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Controlled Monofunctionalization of Molecular Spherical Nucleic Acids on a Buckminster Fullerene Core
[Image: see text] An azide-functionalized 12-armed Buckminster fullerene has been monosubstituted in organic media with a substoichiometric amount of cyclooctyne-modified oligonucleotides. Exposing the intermediate products then to the same reaction (i.e., strain-promoted alkyne–azide cycloaddition,...
Autores principales: | Gulumkar, Vijay, Äärelä, Antti, Moisio, Olli, Rahkila, Jani, Tähtinen, Ville, Leimu, Laura, Korsoff, Niko, Korhonen, Heidi, Poijärvi-Virta, Päivi, Mikkola, Satu, Nesati, Victor, Vuorimaa-Laukkanen, Elina, Viitala, Tapani, Yliperttula, Marjo, Roivainen, Anne, Virta, Pasi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382215/ https://www.ncbi.nlm.nih.gov/pubmed/33998229 http://dx.doi.org/10.1021/acs.bioconjchem.1c00187 |
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