Single-Cell Transcriptomics of Glioblastoma Reveals a Unique Tumor Microenvironment and Potential Immunotherapeutic Target Against Tumor-Associated Macrophage

BACKGROUND: The main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studies investigating the activation status of TAM in GBM are mainly limited to bulk RNA analyses of individual tumor biopsies. The activation states and transcriptional signatures of TAMs in GBM remain p...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Xiaoteng, Wang, Qixue, Zhou, Junhu, Wang, Yunfei, Xu, Can, Tong, Fei, Wang, Hongjun, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382282/
https://www.ncbi.nlm.nih.gov/pubmed/34434898
http://dx.doi.org/10.3389/fonc.2021.710695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382282/
https://www.ncbi.nlm.nih.gov/pubmed/34434898
http://dx.doi.org/10.3389/fonc.2021.710695

Ejemplares similares