HIF1α is required for NK cell metabolic adaptation during virus infection

Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we found upregulation of the metabolic adaptor hypoxia-inducible factor-1α (HIF1α) is a feature of mouse NK cells during murine cytomegalovirus...

Descripción completa

Detalles Bibliográficos
Autores principales: Victorino, Francisco, Bigley, Tarin M, Park, Eugene, Yao, Cong-Hui, Benoit, Jeanne, Yang, Li-Ping, Piersma, Sytse J, Lauron, Elvin J, Davidson, Rebecca M, Patti, Gary J, Yokoyama, Wayne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382296/
https://www.ncbi.nlm.nih.gov/pubmed/34396954
http://dx.doi.org/10.7554/eLife.68484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382296/
https://www.ncbi.nlm.nih.gov/pubmed/34396954
http://dx.doi.org/10.7554/eLife.68484

Ejemplares similares