Cargando…

An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

Cells communicate with their environment via surface proteins and secreted factors. Unconventional protein secretion (UPS) is an evolutionarily conserved process, via which distinct cargo proteins are secreted upon stress. Most UPS types depend upon the Golgi-associated GRASP55 protein. However, its...

Descripción completa

Detalles Bibliográficos
Autores principales: Nüchel, Julian, Tauber, Marina, Nolte, Janica L., Mörgelin, Matthias, Türk, Clara, Eckes, Beate, Demetriades, Constantinos, Plomann, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382303/
https://www.ncbi.nlm.nih.gov/pubmed/34245671
http://dx.doi.org/10.1016/j.molcel.2021.06.017