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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
Cells communicate with their environment via surface proteins and secreted factors. Unconventional protein secretion (UPS) is an evolutionarily conserved process, via which distinct cargo proteins are secreted upon stress. Most UPS types depend upon the Golgi-associated GRASP55 protein. However, its...
Autores principales: | Nüchel, Julian, Tauber, Marina, Nolte, Janica L., Mörgelin, Matthias, Türk, Clara, Eckes, Beate, Demetriades, Constantinos, Plomann, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382303/ https://www.ncbi.nlm.nih.gov/pubmed/34245671 http://dx.doi.org/10.1016/j.molcel.2021.06.017 |
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