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Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design

OBJECTIVES: To identify putative biomarkers that may serve as quantifiable, biological, nonclinical measures of the pharmacodynamic effect of edaravone in amyotrophic lateral sclerosis (ALS) and to report real-world treatment outcomes. METHODS: This is a prospective, observational, longitudinal, mul...

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Detalles Bibliográficos
Autores principales: Berry, James, Brooks, Benjamin, Genge, Angela, Heiman-Patterson, Terry, Appel, Stanley, Benatar, Michael, Bowser, Robert, Cudkowicz, Merit, Gooch, Clifton, Shefner, Jeremy, Westra, Jurjen, Agnese, Wendy, Merrill, Charlotte, Nelson, Sally, Apple, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382414/
https://www.ncbi.nlm.nih.gov/pubmed/34476128
http://dx.doi.org/10.1212/CPJ.0000000000000968