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Destructive Effects of Pyroptosis on Homeostasis of Neuron Survival Associated with the Dysfunctional BBB-Glymphatic System and Amyloid-Beta Accumulation after Cerebral Ischemia/Reperfusion in Rats

Neuroinflammation-related amyloid-beta peptide (Aβ) accumulation after cerebral ischemia/reperfusion (I/R) accounts for cerebral I/R injuries and poststroke dementia. Recently, pyroptosis, a proinflammatory cell death, has been identified as a crucial pathological link of cerebral I/R injuries. Howe...

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Detalles Bibliográficos
Autores principales: Lyu, Zhongkuan, Chan, Yuanjin, Li, Qiyue, Zhang, Qiang, Liu, Kaili, Xiang, Jun, Li, Xiangting, Cai, Dingfang, Li, Yaming, Wang, Bing, Yu, Zhonghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382555/
https://www.ncbi.nlm.nih.gov/pubmed/34434229
http://dx.doi.org/10.1155/2021/4504363