Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1α Increase in Blood-Brain Barrier Disruption after 2-Hour Focal Ischemic Stroke in Rat

We recently showed that inhibition of hypoxia-induced factor-1α (HIF-1α) decreased acute ischemic stroke-induced blood-brain barrier (BBB) damage. However, factors that induce the upregulation of HIF-1α expression remain unclear. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase played a c...

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Detalles Bibliográficos
Autores principales: Wang, Yanping, Shen, Yufei, Yu, Xin, Gu, Jingxia, Zhang, Xiaoling, Zhou, Beiqun, Sun, Yanyun, Xu, Congying, Qian, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382561/
https://www.ncbi.nlm.nih.gov/pubmed/34434231
http://dx.doi.org/10.1155/2021/9928232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382561/
https://www.ncbi.nlm.nih.gov/pubmed/34434231
http://dx.doi.org/10.1155/2021/9928232

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