Cargando…

Role of NADPH Oxidase-Induced Hypoxia-Induced Factor-1α Increase in Blood-Brain Barrier Disruption after 2-Hour Focal Ischemic Stroke in Rat

We recently showed that inhibition of hypoxia-induced factor-1α (HIF-1α) decreased acute ischemic stroke-induced blood-brain barrier (BBB) damage. However, factors that induce the upregulation of HIF-1α expression remain unclear. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase played a c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yanping, Shen, Yufei, Yu, Xin, Gu, Jingxia, Zhang, Xiaoling, Zhou, Beiqun, Sun, Yanyun, Xu, Congying, Qian, Shuxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382561/ https://www.ncbi.nlm.nih.gov/pubmed/34434231 http://dx.doi.org/10.1155/2021/9928232

Ejemplares similares

Inhibition of HIF-1α Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia
por: Shen, Yufei, et al.
Publicado: (2018)

Dl-NBP (Dl-3-N-Butylphthalide) Treatment Promotes Neurological Functional Recovery Accompanied by the Upregulation of White Matter Integrity and HIF-1α/VEGF/Notch/Dll4 Expression
por: Wang, Yanping, et al.
Publicado: (2020)

Role of NADPH Oxidases in Blood–Brain Barrier Disruption and Ischemic Stroke
por: Hernandes, Marina S., et al.
Publicado: (2022)

Pathophysiology and Therapeutic Potential of NADPH Oxidases in Ischemic Stroke-Induced Oxidative Stress
por: Duan, Jinnan, et al.
Publicado: (2021)

Chronic Intermittent Hypoxia-Induced Diaphragm Muscle Weakness Is NADPH Oxidase-2 Dependent
por: Drummond, Sarah E., et al.
Publicado: (2023)

Protective Properties of the Extract of Chrysanthemum on Patients with Ischemic Stroke
por: Zhu, Zhuoying, et al.
Publicado: (2021)

Role of NADPH Oxidase and Xanthine Oxidase in Mediating Inducible VT/VF and Triggered Activity in a Canine Model of Myocardial Ischemia
por: Martins, James B., et al.
Publicado: (2014)

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1
por: Diebold, Isabel, et al.
Publicado: (2010)

Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity
por: Deep, Gagan, et al.
Publicado: (2016)

HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
por: Nanduri, Jayasri, et al.
Publicado: (2015)

Revealing the roles of GORK channels and NADPH oxidase in acclimation to hypoxia in Arabidopsis
por: Wang, Feifei, et al.
Publicado: (2017)

Focal Ischemic Injury with Complex Middle Cerebral Artery in Stroke-Prone Spontaneously Hypertensive Rats with Loss-Of-Function in NADPH Oxidases
por: Yao, Hiroshi, et al.
Publicado: (2015)

NADPH Oxidase and Neurodegeneration
por: Hernandes, Marina S, et al.
Publicado: (2012)

Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea
por: Nair, Deepti, et al.
Publicado: (2011)

Hypoxia-induced pulmonary vasoconstriction of intra-acinar arteries is impaired in NADPH oxidase 4 gene-deficient mice
por: Murtaza, Ghulam, et al.
Publicado: (2018)

Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis
por: Wen, Su-Ying, et al.
Publicado: (2017)

NADPH oxidase 2 is necessary for chronic intermittent hypoxia‐induced sternohyoid muscle weakness in adult male mice
por: Drummond, Sarah E., et al.
Publicado: (2022)

Polychlorinated Biphenyls Disrupt Intestinal Integrity via NADPH Oxidase-Induced Alterations of Tight Junction Protein Expression
por: Choi, Yean Jung, et al.
Publicado: (2010)

Oxidative Injury in Ischemic Stroke: A Focus on NADPH Oxidase 4
por: Li, Ganglei, et al.
Publicado: (2022)

Flagellin-induced NADPH oxidase 4 activation is involved in atherosclerosis
por: Kim, Jinoh, et al.
Publicado: (2016)

Involvement of NADPH oxidases in alkali burn-induced corneal injury
por: GU, XUE-JUN, et al.
Publicado: (2016)

NADPH Oxidase Isoforms Are Involved in Glucocorticoid-Induced Preosteoblast Apoptosis
por: Bai, Shu-Cai, et al.
Publicado: (2019)

NADPH oxidase–induced oxidative stress in the eyes of hypertensive rats
por: Santana-Garrido, Álvaro, et al.
Publicado: (2021)

NADPH Oxidase-Derived ROS Induced by Chronic Intermittent Hypoxia Mediates Hypersensitivity of Lung Vagal C Fibers in Rats
por: Yang, Chang-Huan, et al.
Publicado: (2016)

NADPH oxidase 4 mediates TGF-β1/Smad signaling pathway induced acute kidney injury in hypoxia
por: Cho, Sungkwon, et al.
Publicado: (2019)

Cyclic stretch induced oxidative stress by mitochondrial and NADPH oxidase in retinal pigment epithelial cells
por: Liang, Xida, et al.
Publicado: (2019)

NADPH Oxidases and Their Role in Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

NADPH Oxidases in Pain Processing
por: Kallenborn-Gerhardt, Wiebke, et al.
Publicado: (2022)

NADPH Oxidases in Aortic Aneurysms
por: Salmon, Morgan
Publicado: (2022)

NADPH Oxidase: a Target for the Modulation of the Excessive Oxidase Damage Induced by Overtraining in Rat Neutrophils
por: Dong, Jingmei, et al.
Publicado: (2011)

NADPH Oxidase as a Therapeutic Target for Oxalate Induced Injury in Kidneys
por: Joshi, Sunil, et al.
Publicado: (2013)

Modulation of Radiation-Induced NADPH Oxidases in Rat’s Heart Tissues by Melatonin
por: Aryafar, Tayebeh, et al.
Publicado: (2021)

HIF-1α-Mediated, NADPH Oxidase-Derived ROS Contributes to Laryngeal Airway Hyperreactivity Induced by Intermittent Hypoxia in Rats
por: Lin, You Shuei, et al.
Publicado: (2020)

Elimination of NADPH Oxidase Activity Promotes Reductive Stress and Sensitizes the Heart to Ischemic Injury
por: Yu, Qiujun, et al.
Publicado: (2014)

Natural Compounds as Modulators of NADPH Oxidases
por: Maraldi, Tullia
Publicado: (2013)

NADPH Oxidases and Mitochondria in Vascular Senescence
por: Salazar, Gloria
Publicado: (2018)

NADPH oxidases: Current aspects and tools
por: Schröder, Katrin
Publicado: (2020)

Architecture of the NADPH oxidase family of enzymes
por: Ogboo, Blessing C., et al.
Publicado: (2022)

(Poly)phenols and the regulation of NADPH oxidases
por: Fraga, Cesar G., et al.
Publicado: (2023)

NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology
por: Schiavone, S, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_fomvfej8ler75alot6l6ahpka9