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Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target

Niemann-Pick type C1 (NPC1) receptor is an endosomal membrane protein that regulates intracellular cholesterol traffic. This protein has been shown to play an important role for several viruses. It has been reported that SARS-CoV-2 enters the cell through plasma membrane fusion and/or endosomal entr...

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Detalles Bibliográficos
Autores principales: García-Dorival, Isabel, Cuesta-Geijo, Miguel Ángel, Barrado-Gil, Lucía, Galindo, Inmaculada, Garaigorta, Urtzi, Urquiza, Jesús, Puerto, Ana del, Campillo, Nuria E., Martínez, Ana, Gastaminza, Pablo, Gil, Carmen, Alonso, Covadonga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382594/
https://www.ncbi.nlm.nih.gov/pubmed/34450201
http://dx.doi.org/10.1016/j.antiviral.2021.105167