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HLA class I genes modulate disease risk and age at onset together with DR-DQ in Chinese patients with insulin-requiring type 1 diabetes

AIMS/HYPOTHESIS: The study aimed to investigate the effects of HLA class I genes on susceptibility to type 1 diabetes with different onset ages, in addition to the well-established effects of HLA class II genes. METHODS: A total of 361 patients with type 1 diabetes (192 patients with onset <18 ye...

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Detalles Bibliográficos
Autores principales: Jiang, Ziyu, Ren, Wenqian, Liang, Hua, Yan, Jinhua, Yang, Daizhi, Luo, Sihui, Zheng, Xueying, Lin, Guo-Wang, Xian, Yingxin, Xu, Wen, Yao, Bin, Noble, Janelle A., Bei, Jin-Xin, Groop, Leif, Weng, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382651/
https://www.ncbi.nlm.nih.gov/pubmed/34023962
http://dx.doi.org/10.1007/s00125-021-05476-6