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Single cell organization and cell cycle characterization of DNA stained multicellular tumor spheroids
Multicellular tumor spheroids (MCTSs) can serve as in vitro models for solid tumors and have become widely used in basic cancer research and drug screening applications. The major challenges when studying MCTSs by optical microscopy are imaging and analysis due to light scattering within the 3-dimen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382712/ https://www.ncbi.nlm.nih.gov/pubmed/34426602 http://dx.doi.org/10.1038/s41598-021-96288-6 |