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Single cell organization and cell cycle characterization of DNA stained multicellular tumor spheroids

Multicellular tumor spheroids (MCTSs) can serve as in vitro models for solid tumors and have become widely used in basic cancer research and drug screening applications. The major challenges when studying MCTSs by optical microscopy are imaging and analysis due to light scattering within the 3-dimen...

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Detalles Bibliográficos
Autores principales: Olofsson, Karl, Carannante, Valentina, Takai, Madoka, Önfelt, Björn, Wiklund, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382712/
https://www.ncbi.nlm.nih.gov/pubmed/34426602
http://dx.doi.org/10.1038/s41598-021-96288-6