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Temozolomide Drives Ferroptosis via a DMT1-Dependent Pathway in Glioblastoma Cells

PURPOSE: Temozolomide is used in first-line treatment for glioblastoma. However, chemoresistance to temozolomide is common in glioma patients. In addition, mechanisms for the anti-tumor effects of temozolomide are largely unknown. Ferroptosis is a form of programmed cell death triggered by disturbed...

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Detalles Bibliográficos
Autores principales: Song, Qingxin, Peng, Shanxin, Sun, Zhiqing, Heng, Xueyuan, Zhu, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382730/
https://www.ncbi.nlm.nih.gov/pubmed/34427071
http://dx.doi.org/10.3349/ymj.2021.62.9.843