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The paraventricular thalamus provides a polysynaptic brake on limbic CRF neurons to sex-dependently blunt binge alcohol drinking and avoidance behavior in mice

Bed nucleus of the stria terminalis (BNST) neurons that synthesize corticotropin-releasing factor (CRF) drive binge alcohol drinking and anxiety. Here, we found that female C57BL/6J mice binge drink more than males and have greater basal BNST(CRF) neuron excitability and synaptic excitation. We iden...

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Detalles Bibliográficos
Autores principales: Levine, Olivia B., Skelly, Mary Jane, Miller, John D., Rivera-Irizarry, Jean K., Rowson, Sydney A., DiBerto, Jeffrey F., Rinker, Jennifer A., Thiele, Todd E., Kash, Thomas L., Pleil, Kristen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382748/
https://www.ncbi.nlm.nih.gov/pubmed/34426574
http://dx.doi.org/10.1038/s41467-021-25368-y