A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis

Genome-wide association studies (GWAS) have identified loci for kidney disease, but the causal variants, genes, and pathways remain unknown. Here we identify two kidney disease genes Dipeptidase 1 (DPEP1) and Charged Multivesicular Body Protein 1 A (CHMP1A) via the triangulation of kidney function G...

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Detalles Bibliográficos
Autores principales: Guan, Yuting, Liang, Xiujie, Ma, Ziyuan, Hu, Hailong, Liu, Hongbo, Miao, Zhen, Linkermann, Andreas, Hellwege, Jacklyn N., Voight, Benjamin F., Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382756/
https://www.ncbi.nlm.nih.gov/pubmed/34426578
http://dx.doi.org/10.1038/s41467-021-25377-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382756/
https://www.ncbi.nlm.nih.gov/pubmed/34426578
http://dx.doi.org/10.1038/s41467-021-25377-x

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