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Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96‑Transwell air–liquid interface model

In order to circumvent the limited access and donor variability of human primary alveolar cells, directed differentiation of human pluripotent stem cells (hiPSCs) into alveolar-like cells, provides a promising tool for respiratory disease modeling and drug discovery assays. In this work, a unique, m...

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Detalles Bibliográficos
Autores principales: Bluhmki, Teresa, Traub, Stefanie, Müller, Ann-Kathrin, Bitzer, Sarah, Schruf, Eva, Bammert, Marie-Therese, Leist, Marcel, Gantner, Florian, Garnett, James P, Heilker, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382767/
https://www.ncbi.nlm.nih.gov/pubmed/34426605
http://dx.doi.org/10.1038/s41598-021-96565-4