Reactivity of Thiol-Rich Zn Sites in Diacylglycerol-Sensing PKC C1 Domain Probed by NMR Spectroscopy

Conserved homology 1 (C1) domains are peripheral zinc finger domains that are responsible for recruiting their host signaling proteins, including Protein Kinase C (PKC) isoenzymes, to diacylglycerol-containing lipid membranes. In this work, we investigated the reactivity of the C1 structural zinc si...

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Detalles Bibliográficos
Autores principales: Cole, Taylor R., Igumenova, Tatyana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382798/
https://www.ncbi.nlm.nih.gov/pubmed/34447788
http://dx.doi.org/10.3389/fmolb.2021.728711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382798/
https://www.ncbi.nlm.nih.gov/pubmed/34447788
http://dx.doi.org/10.3389/fmolb.2021.728711

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