Sulforaphane inhibits self-renewal of lung cancer stem cells through the modulation of sonic Hedgehog signaling pathway and polyhomeotic homolog 3

Sulforaphane (SFN), an active compound in cruciferous vegetables, has been characterized by its antiproliferative capacity. We investigated the role and molecular mechanism through which SFN regulates proliferation and self-renewal of lung cancer stem cells. CD133(+) cells were isolated with MACs fr...

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Detalles Bibliográficos
Autores principales: Wang, Fanping, Sun, Yanwei, Huang, Xiaoyu, Qiao, Caijuan, Zhang, Wenrui, Liu, Peijun, Wang, Mingyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382806/
https://www.ncbi.nlm.nih.gov/pubmed/34424425
http://dx.doi.org/10.1186/s13568-021-01281-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382806/
https://www.ncbi.nlm.nih.gov/pubmed/34424425
http://dx.doi.org/10.1186/s13568-021-01281-x

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