The MS Remyelinating Drug Bexarotene (an RXR Agonist) Promotes Induction of Human Tregs and Suppresses Th17 Differentiation In Vitro

The retinoid X receptor agonist bexarotene promotes remyelination in patients with multiple sclerosis. Murine studies have also demonstrated that RXR agonists have anti-inflammatory effects by enhancing the ability of all-trans-retinoic acid (atRA) to promote T-regulatory cell (Treg) induction and r...

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Detalles Bibliográficos
Autores principales: Gaunt, Christopher M., Rainbow, Daniel B., Mackenzie, Ruairi J., Jarvis, Lorna B., Mousa, Hani S., Cunniffe, Nicholas, Georgieva, Zoya, Brown, J. William, Coles, Alasdair J., Jones, Joanne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382874/
https://www.ncbi.nlm.nih.gov/pubmed/34447379
http://dx.doi.org/10.3389/fimmu.2021.712241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382874/
https://www.ncbi.nlm.nih.gov/pubmed/34447379
http://dx.doi.org/10.3389/fimmu.2021.712241

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