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Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

OBJECTIVE: Insulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in 45,X/46,XY mosaicism. The aim was to examine serum concentrations and gonadal expression of INSL3 in 45,X/46,XY mosaicism. METHODS:...

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Detalles Bibliográficos
Autores principales: Ljubicic, Marie Lindhardt, Jørgensen, Anne, Aksglaede, Lise, Nielsen, John Erik, Albrethsen, Jakob, Juul, Anders, Johannsen, Trine Holm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382946/
https://www.ncbi.nlm.nih.gov/pubmed/34447353
http://dx.doi.org/10.3389/fendo.2021.709954