YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1

Ventilation is dependent upon pulmonary alveoli lined by two major epithelial cell types, alveolar type-1 (AT1) and 2 (AT2) cells. AT1 cells mediate gas exchange while AT2 cells synthesize and secrete pulmonary surfactants and serve as progenitor cells which repair the alveoli. We developed transgen...

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Detalles Bibliográficos
Autores principales: Gokey, Jason J., Snowball, John, Sridharan, Anusha, Sudha, Parvathi, Kitzmiller, Joseph A., Xu, Yan, Whitsett, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383002/
https://www.ncbi.nlm.nih.gov/pubmed/34466790
http://dx.doi.org/10.1016/j.isci.2021.102967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383002/
https://www.ncbi.nlm.nih.gov/pubmed/34466790
http://dx.doi.org/10.1016/j.isci.2021.102967

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