Proteomics Mapping of the ISGylation Landscape in Innate Immunity
During infection, pathogen sensing and cytokine signaling by the host induce expression of antimicrobial proteins and specialized post-translational modifications. One such protein is ISG15, a ubiquitin-like protein (UBL) conserved among vertebrates. Similar to ubiquitin, ISG15 covalently conjugates...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383068/ https://www.ncbi.nlm.nih.gov/pubmed/34447387 http://dx.doi.org/10.3389/fimmu.2021.720765 |