Proteomics Mapping of the ISGylation Landscape in Innate Immunity

During infection, pathogen sensing and cytokine signaling by the host induce expression of antimicrobial proteins and specialized post-translational modifications. One such protein is ISG15, a ubiquitin-like protein (UBL) conserved among vertebrates. Similar to ubiquitin, ISG15 covalently conjugates...

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Detalles Bibliográficos
Autores principales: Thery, Fabien, Eggermont, Denzel, Impens, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8383068/
https://www.ncbi.nlm.nih.gov/pubmed/34447387
http://dx.doi.org/10.3389/fimmu.2021.720765